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Description

Prior to the initiation of valproic acid therapy, evaluation for UCD should be considered in the following patients: 1) those with a history of unexplained encephalopathy or coma, encephalopathy associated with a protein load, pregnancy-related or postpartum encephalopathy, unexplained mental retardation, or history of elevated plasma ammonia or glutamine

Core Function: Fatty Acid Transport L-carnitine shuttles long-chain fatty acids into mitochondria for beta-oxidation, breaking them down into acetyl-CoA units that feed the Krebs cycle for ATP production