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In mice, a single lipid nanoparticle delivery of editor mRNAs targeting PCSK9 achieved nearly 50% reduction in circulating PCSK9 levels for a year, with silencing maintained after liver regeneration

Cell 106 , 157169 (2001)

Nymphal immersion test (NIT) Unfed nymphs were immersed in a microcentrifuge tube containing 1 ml of the test materials for 2 min and then dried on filter paper

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