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4.1 Oxidative stress and mitochondrial damage Oxidative stress and subsequent mitochondrial damage are the key pathological initiating factors of toxicity-induced hepatic metabolic barrier damage

MRI with T1 and T2 mapping can detect copper deposition with greater sensitivity than ultrasound, though cost limits its use as a screening tool [7]

Judging distances of objects may be more difficult with this method, and it can be uncomfortable for some people

For example, the membrane lipid composition regulates the processes of ferroptosis and necroptosis

A good antioxidant should specifically quench free radicals, chelate redox metals, interact with other antioxidants within an antioxidant network, have a positive effect on gene expression, be readily absorbed, have a concentration in tissues and biofluids at a physiologically relevant level, act in both aqueous and/or membrane domains (2)