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They are effective for treatment-resistant depression, atypical depression, and panic disorders

Their half-lives are intermediate (TRF) or extremely short (RBP), theoretically offering different values for dynamic monitoring (84)

Pain 161(1):S122S126

It also modulates non-coding RNAs by targeting the HOTAIR/miR-34a axis in breast cancer, upregulating let-7b to suppress cyclin D1 in melanoma, and synergizing with miR-137 upregulation in glioma (Zhao et al., 2023