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Similarly, high concentrations of ions, like the sodium and chloride in saline, can interfere with the hydration shell around the peptide and promote aggregation, where peptide molecules clump together into an inactive, insoluble mass

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Cells were then washed with PBS, blocked in 1% bovine serum albumin for 30 min and incubated with anti-p-STAT3 Tyr705 (Santa Cruz Biotechnology) or anti-p-NF-B/p65 Ser536 antibody (Cell Signaling) in 0.1% bovine serum albumin at 4 C overnight

This is fundamental peptide safety practice

Q: Why add cagrilintide to a GLP1/GIP/glucagon approach