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Oxidative stress occurs when there is an imbalance between the production of free radicals and the bodys ability to detoxify them

PubMed CrossRef Maisel NC, Blodgett JC, Wilbourne PL, et al

2, June 2013, pp

Their significance in the mechanism of breast cancer tumorigenesis is highlighted by their proposal as potential biomarkers of its prognosis (discussed in Section 5)