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Yeah, I got to think about that some more though

Mol Cancer 16:13

A gut microbiome that lacks an abundance of histamine degrading Bifidobacteria leaves allergic features unopposed (Dev et al., 2008)

JAMA, 312(4), 380389.

Effective patient stratification should extend beyond conventional biomarkers to incorporate dominant resistance pathways and baseline immune contexture, thereby enabling the selection of rationally designed combination therapies tailored to intercept specific immunoediting trajectories