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Recent studies have found that it also plays a role in ferroptosis

4.5 KRAS mutation in pancreatic cancer diagnosis and prognosis As one of the most devastating digestive system cancers, PDAC is characterized by a lack of specific symptoms, fast progression, and poor prognosis ( KRAS mutation and cytopathology increased the sensitivity, accuracy, and negative predictive value of pancreatic cancer diagnosis and molecular subtype classification

Clin Microbiol Rev 26(4):744758

All thesis works have been done at the Medicinal Plants Research Center of Shahrekord University of Medical Sciences

Moreover, we highlight recent therapeutic advances including the Food and Drug Administration (FDA) approval of resmetirom in 2024 and other promising agents currently in phase 2/3 trials providing a timely and translationally relevant overview that bridges current scientific evidence with emerging clinical applications in MASLD