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These complexities are further underscored by a recent report by Soriani et al., which suggests that CD38 can act as a decoy for extracellular cGAMP, a mediator of innate immunity

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To date, many genes have been identified that are linked to increased risk of developing ASD, and among these genes, 20 of them encode proteins involved in Rho signaling pathways (Guo et al., 2020), underscoring the importance of Rho proteins in the pathogenetic process of ASD