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Paraffin-embedded specimens were finally stained with hematoxylin-eosin (H&E), Wheat Germ Agglutinin (WGA), Masson, Periodic acid-Schiffs (PAS), selected antibodies (connexin-43

doi: 10.1007/s11011-015-9649-1

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They're the result of several overlapping hormonal, neurological and lifestyle factors which is why they can feel so hard to pin down