bpc-157 clinical trial nct02637284

bpc-157 clinical trial nct02637284 status BPC-157 FDA Approval Status 2026: Trials Stable Gastric Pentadecapeptide BPC 157

Name: bpc-157 clinical trial nct02637284 status BPC-157 FDA Approval Status 2026: Trials Stable Gastric Pentadecapeptide BPC 157
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doi: 10.1084/jem.20111497

At a glance Direct interaction data / none published in human trials as of May 2026 BPC-157 primary mechanism / nitric oxide system modulation, angiogenesis, and GI cytoprotection Ashwagandha primary mechanism / HPA-axis modulation, cortisol reduction, withanolide-driven adaptogenesis Overlap concern / both influence the hypothalamic-pituitary-adrenal and hypothalamic-pituitary-thyroid axes Suggested dose separation / 30 to 60 minutes between oral ashwagandha and oral BPC-157 Monitoring labs / TSH, free T4, morning cortisol at baseline and every 8 to 12 weeks Ashwagandha cortisol reduction / 30.5% decrease in serum cortisol vs