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The authors of the meta-analysis examined if maternal serum homocysteine levels, folic acid supplementation, or gestational age could explain the variation in the results, but none significantly explained the difference between studies

However, consumption of any type of vegetarian diet dramatically increases the prevalence of vitamin B 12 deficiency in individuals across all age groups (127, 128)

Side Effects and Safety Considerations Like most compounds that act on central neurotransmitters, Tesofensine carries a dose-dependent risk profile