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The Paneth cells in the epithelium produce defensins and other antimicrobial peptides

In contrast to HmbR, which preferentially but not exclusively recognizes human hemoglobin, TbpA/TbpB and LbpA/LbpB recognize exclusively human transferrin and lactoferrin, respectively, and this selectivity strongly contributes to the narrow host spectrum of the meningococcus (Perkins-Balding et al., 2004)

MUC1 cell surface mucin is a critical element of the mucosal barrier to infection

279,280,281 Conversely, dysbiosis shifts this balance

The comparative absence of these enzymes has led to the perception that -cells are vulnerable to oxidative damage (40)