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Metabolic Rewiring: By stopping the conversion of nicotinamide (NAM) into 1-methylnicotinamide (1-MNA), the cell is forced to recycle NAM into NAD+

The dose chosen was based on an initial dose escalation study (ranging from 10 mg/kg/day to a total dose of 150 mg/kg/day) in DIO mice (n=2)

link Stier H, Vos E, Kenley D

Research Data Stack Suggestions AOD-9604 + MOTS-c Synergistic activation of AMPK and mitochondrial oxidation for enhanced energy expenditure AOD-9604 + L-Carnitine Amplifies fat transport into mitochondria for improved fatty acid utilization AOD-9604 + Tesamorelin Dual-pathway lipolysis stimulation (GH-releasing + GH fragment synergy) AOD-9604 + Rttrutd / rztd Complementary metabolic pathways for obesity and insulin control research