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Gut Microbiota-Derived Trimethylamine N-Oxide Contributes to Abdominal Aortic Aneurysm Through Inflammatory and Apoptotic Mechanisms

Intracellular trapping of the selective phosphoglycerate dehydrogenase (PHGDH) inhibitor BI-4924 disrupts serine biosynthesis

MK-677 is different because it is a non-peptide oral secretagogue that survives digestion and stimulates ghrelin-related signaling

Additionally, GGCT knockdown concomitantly reduced 5- oxoproline (5-OP) levels in MHCC97H cells, consistent with 5-OP being the direct enzymatic product of GGCT activity, and exogenous 5-OP rescued proliferation under Gln-deprived conditions (Fig