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The resulting acyl-phosphate intermediate undergoes nucleophilic attack by the -amino group of cysteine, which may be activated by an active site glutamate

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CO 2 lasers can target unwanted pigmentation, but they are not effective in reducing vascular lesions like spider veins or rosacea

The liver was further perfused with the perfusion buffer II (8.3 g/L NaCl, 0.5 g/L KCl, and 2.4 g/L HEPES), which was followed by collagenase type IV medium at 37 C

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