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Identification of the therapeutic features of NS came from researches in various fields starting in the early 1970s [11]

doi:10.26442/terarkh201890389-95 Fundam Clin Pharmacol

doi: 10.3389/fmicb.2022.815044 352 WillettJ

The pathological hallmarks of PD include the misfolding and aggregation of -syn into LBs, leading to the degeneration of dopaminergic neurons in the substantia nigra pars compacta and the depletion of striatal dopamine