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Tumor-induced competition for glutamine exerts a formidable impact on immune cells, as cancer cells' secretion of glutamate not only disrupts T cell activation and promotes an immunosuppressive phenotype in neutrophils and MDSCs but also facilitates a shift towards an M2 macrophage phenotype

Juvenile-onset systemic lupus erythematosus: different clinical and serological pattern than adult-onset systemic lupus erythematosus

M1 microglia release neurotoxic and inflammatory factors such as IL-6, IL-1, and TNF-, contributing to neuronal damage and death, while M2 microglia secrete neurotrophic factors including BDNF, IL-4, and IL-10, fostering neuronal growth and protection (51)

Dietary antioxidants and dementia in a population-based case-control study among older people in South Germany

This hormonal imbalance not only disrupts the menstrual cycle and ultimately leads to its cessation but also triggers a range of multisystem symptoms, including vasomotor disturbances (such as hot flashes and night sweats), mastalgia, musculoskeletal pain, vaginal dryness, fatigue and neuropsychiatric symptoms such as anxiety, depression and cognitive impairment (4-7)