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Br J Dermatol 187(1):8998

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Malonyl-CoA is the product of the carboxylation of acetyl-CoA by the enzyme acetyl-CoA carboxylase (ACC), the first step in de novo fatty acid synthesis (Ameer et al., 2014), and it acts as a potent inhibitor of mammalian -oxidation in the liver (McGarry and Brown, 1997)

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