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Omega-3 fatty acids exert beneficial effects on neurological diseases by acting on neuronal cells and inhibiting the formation of proinflammatory cytokines involved in CIPN [135]

Excessive reduction of ROS may impair these fundamental physiological functions, potentially weakening host defense mechanisms and disrupting normal skin repair processes

Biomarkers and Metabolic Factors Influencing Glutathione Status Glutathione levels are influenced by dietary cysteine and methionine intake, oxidative stress burden, liver synthetic function, and age-related decline

In the first, it undergoes oxidation within the TCA cycle [often called the Szent-GyrgyiKrebs cycle, acknowledging the Nobel Prize (1937) winning contributions of Albert Szent-Gyrgyi in identifying the fumarate, malate and oxaloacetate forming reactions towards the end of the cycle, and those of Hans Adolf Krebs, Nobel Prize (1953), for elucidating the details of the overall cycle], ultimately being converted to pyruvate and lactate in the cytosol through a metabolic process known as glutaminolysis (represented by blue arrows) (Albert Szent-Gyrgyi FactsNobelPrize.org n.d

Jarisch-Herxheimer Reaction After Benzathine Penicillin G Treatment in Adults With Early Syphilis: Secondary Analysis of a Randomized Clinical Trial