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Even though gene expression studies are required to understand the influence of DNA methylation of the above-mentioned genes, the differences in DNA methylation in CB and CuB samples are indicative of a potential regulatory mechanism adapted by OA G20 to cope with metal stress

These data were confirmed in similar murine models in which exogenous application of recombinant IL-17A stimulated pathological changes associated with increased plaque instability, and, vice versa, IL-17A inhibition produced a regression of atherosclerosis (100103)

This expands the genetic code, beyond the twenty canonical amino acids found in nature, to include an unnatural amino acid as well

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CpGs are underrepresented in the genome and show a tendency to concentrate at specific clusters, called CpG islands