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The quantity and quality of DNA were assessed by measuring the concentration of DNA and the ratio of the UV absorption at 280 nm to 260 nm using a Nanodrop 1000 UV/Vis spectrophotometer (Thermo Fisher Scientific, Waltham, MA, USA)

Commonly reported side effects can include mild pain or some bruising where the injection is given, allergic reactions such as rashes or itching, and occasionally nausea or stomach discomfort

Alzheimer, Parkinson, ferroptosis-related events, and Huntington disease, amyotrophic lateral sclerosis, Friedreich ataxia, traumatic brain injury, stroke, periventricular leukomalacia), namely iron accumulation in specific brain neuronal areas, reduced GSH activity or content, reduced GPX4 protein levels and cell loss.43 For instance, iron accumulates in areas susceptible to Alzheimer's disease that show plaque formation, even before aggregation of A and tau proteins which is also favored by oxidative stress.4446 Ferroptosis markers Therapeutic interventions benefit from the availability of biomarkers that provide information on the state of activation of the therapeutic target and monitor the effectiveness of the therapeutic intervention in suppressing the target