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While folate depletion induced differentiation in both cell lines as measured by increased CD11b surface expression (Figures 1C and 1D), deprivation of riboflavin had negligible effects on CD11b levels

ANTIDEPRESSANT WITHDRAWAL SYMPTOMS PHYSICAL SYMPTOMS Gastrointestinal: abdominal pain, diarrhoea, nausea, vomiting Influenza-like: fatigue, headache, muscle pain, weakness, sweating, chills, palpitations Sleep disturbance: insomnia, vivid dreams, nightmares Sensory disturbances: dizziness, light-headedness, vertigo, pins and needles, electric shock sensations Motor disorders: tremor, loss of balance, muscle stiffness, abnormal movements PSYCHOLOGICAL SYMPTOMS Anxiety, agitation Crying spells Irritability Overactivity Aggression Depersonalisation Memory Problems Confusion Lowered mood Beta-blockers In a few cases, severe palpitations, muscle tremors or motor jerks develop during benzodiazepine withdrawal and hinder progress

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Preparing everything in advance helps reduce handling time and minimizes opportunities for contamination

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