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as indicated by increased peroxidation of lipids and H 2 O 2 concentration

Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonins neuroprotective activity after focal cerebral ischemia in mice

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Neuroprotective mechanisms Many studies have shown that the epileptogenic state involves complex molecular pathways in which oxidative stress and mitochondrial dysfunction may exert important roles in neuronal programmed/controlled (apoptosis) or uncontrolled/passive (necrosis) cell death 42

Activation of KATP Channels by H2S in Rat Insulin-Secreting Cells and the Underlying Mechanisms