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[11] Function [edit] NADPH provides the reducing agents, usually hydrogen atoms, for biosynthetic reactions and the oxidation-reduction involved in protecting against the toxicity of reactive oxygen species (ROS), allowing the regeneration of glutathione (GSH)

Ultimately, the expressed cytoskeletal-remodeling and ECM-degrading proteases enable tumor cells to invade the surrounding tissue (61, 62)

doi: 10.1007/s00421-009-0998-5