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The authors extend their appreciation to the Deanship of Scientific Research and Graduate Studies at King Khalid University for funding this work through a Large Group Research Project under grant number RGP.2/189/46

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Mehrvarz Sarshekeh A, Loree J, Lima Pereira AA, Raghav KPS, Lam M, Advani SM, Davis JS, Dasari A, Morris VK, Menter D, Eng C, Shaw KR, Broaddus R, Routbort M, Luthra R, Maru DM, Overman MJ, Meric-Bernstam F, Kopetz S

Elucidating how mtDNA alterations engage these layers in a context-dependent manner will be critical for defining when metabolic and immunologic rewiring promotes immune evasion versus antitumor immunity