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Aspiration to check whether the needle is in a blood vessel is not necessary (PHE, 2013)

It should be mentioned that according to the latest systematic review and meta-analysis performed by Duailibi et al., NAC was superior to placebo in diminishing craving symptoms in SUD [84]

However, the approval of nusinersen has generated a number of immediate and substantial medical, ethical and financial implications that have the potential to resonate beyond the specific treatment of SMA