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J Med Chem 45(12):2484-93, 2002

Tranexamic Acid - an Amino Acid derivative that inhibits inflammation and reduces the appearance of stubborn dark spots that do not respond to other skin lightening ingredients

Endpoint fluorescence was read using a plate reader (Spectramax M3, Molecular Devices, Sunnyvale, CA, USA) to obtain reduced GSH

In cells, the presence of MTs confers resistance to the harmful effects of Cd, but the inability to produce MTs makes cells more susceptible to the metals effects (53)