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Indeed, secretion of alanine is higher in melanoma cell lines compared to normal melanocytes and is quite significant in human colon carcinoma tumors [35,64]

PMID: 9326189

Research to date, particularly in AMS and related hypoxic conditions, indicates that TCM and TM interventions, mainly through herbal medicines, may exert beneficial effects on HACE by regulating inflammatory responses, reducing oxidative stress, improving cerebral blood flow and microcirculation, providing neuroprotection, and potentially affecting cell metabolism (Wang et al., 2023)

Polydatin ameliorates renal ischemia/reperfusion injury by decreasing apoptosis and oxidative stress through activating sonic hedgehog signaling pathway