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In a rat myocardial I/R model, AS-IV administration significantly improved left ventricular systolic pressure, FS, and EF, while decreasing left ventricular end-diastolic pressure

Glucuronidation is the only conjugation reaction performed by microsomal enzymes

285 It can cross the blood-brain barrier, resulting in enhanced bioavailability, and research suggests it enhances GABA receptor activity in the brains hippocampus and exerts neuroprotective effects in the central nervous system

10.1007/s11095-012-0674-z 132 PolerN.BadolatoM.PerriF.CarulloG.AielloF

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