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Mutlu-Turkoglu U, Ilhan E, Oztezcan S, Kuru A, Aykac-Toker G, Uysal M

10.1016/j.apjtb.2017.08.005 Asian Pac J Trop Bio

Precision trials targeting specific PD subtypes (e.g., PINK1/Parkin mutations) and exploration of optimal dosing ratios for combination therapies (e.g., NTFs signaling activators + mitochondrial-targeted antioxidants) may help improve translational success, though such strategies require careful design to address complexity in patient heterogeneity and potential drug-drug interactions

Biology Reports 48 (1), 927939

Weeks 21 through 32: the six-month mark and beyond The six-month milestone is the benchmark that clinical trials use most frequently when reporting semaglutide outcomes