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The advantage of the KR distance metric is that it compares gene assemblage distributions on a phylogenetic tree (of 16S rRNA or other genes), in units of nucleotide substitutions per site, and is therefore a biologically meaningful approach to comparing communities

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In contrast, subsequent treatments (PBS + laser (808 nm, 1 W/cm 2 ), PDA, PDA@Pt, PDA@Pt + laser (808 nm, 1 W/cm 2 )) led to a downregulation of P65 expression and a gradual inhibition of the NF-B signaling pathway