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1492-C ALANINE AMINOTRANSFERASE TO QUANTITATIVE HBsAg RATIO INDEPENDENTLY PREDICTS LONG-TERM HBsAg SEROCLEARANCE AFTER ENTECAVIR CESSATION IN CHINESE HEPATITIS B PATIENTS Ryan Hin-Man Leung 1 , Rex Wan-Hin Hui 1 , Lung Yi Mak 1,2 , Kevin Sze Hang Liu 1 , Danny Ka-Ho Wong 1,2 , James Fung 1,2 , Wai-Kay Seto 2,3,4 and Man-Fung Yuen 2,5 , (1)Department of Medicine, School of Clinical Medicine, the University of Hong Kong, Hong Kong SAR, (2)State Key Laboratory of Liver Research, the University of Hong Kong, Hong Kong SAR, (3)Department of Medicine, School of Clinical Medicine, the University of Hong Kong, (4)Department of Medicine, the University of Hong Kong-Shenzhen Hospital, Shenzhen, China, (5)Department of Medicine, Queen Mary Hospital, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, Hong Kong, China Background: Nucleos(t)ide analogue cessation in chronic hepatitis B (CHB) may induce hepatitis B surface antigen (HBsAg) seroclearance

This might even explain why the changes in HbA1c observed in DG have shown limited effect sizes

UGC/GEN/562/3), NSFC-RGC Joint Research Scheme (N_CUHK448/23), RGC General Research Fund (CUHK14122725), the CUHK Direct Research Grant (2024.066), and the Hebei Provincial Major Science and Technology Support Plan International Scientific and Technological Cooperation/Hong Kong, Macau, and Taiwan Science and Technology Cooperation Project (No

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JCI Insight, 3 (11) e121000