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However, non-motor symptoms also play a role toward the diseases burden, with some appearing before clinical diagnosis and others emerging decades after motor deficits (Kalia and Lang, 2015

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Follow-up evaluations include repeat testing of thyroid function, nutrient levels, adrenal function, and inflammatory markers to track progress and adjust treatment plans

But then you look at the other things that can impact that conversion, and youre looking at things like thyroid disorders, other nutrient deficiencies, for example, protein deficiency, zinc deficiency, vitamin E deficiency, conditions like oxidative, stress which we associate with the general wear and tear of aging, but also many disease states