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Sci Immunol (2016) 1:20160805

Magnetic resonance imaging of cancer metabolism with hyperpolarized (13)C-labeled cell metabolites

This is because the breakdown of glucose blocks the ability of these peptides to signal, thus making them ineffective

Contrarily, cells with silenced miR-124 exhibited increased expression levels of STAT 3 in both mRNA and protein formats (Zhang et al., 2023)

Additionally, excessive dosing or delayed metabolism can trigger a Phase II transition, resulting in a deeper block that functionally resembles non-depolarizing paralysis