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Iron accumulation-induced ROS, such as superoxide anion (O 2 -) and hydroxyl radical (OH), possess an unpaired electron at their outer orbit which allows them to react with all cellular components including proteins, lipids and nucleic acid

Neurodegenerative Disease & Aging GSH levels decline with age and in neurodegenerative conditions, including Alzheimers, Parkinsons, and Huntingtons disease, in addition to stroke