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Notably, these pharmacological features are conceptually consistent with the traditional Chinese medicine theory of deficiencystasisturbidity, which shows notable parallels with contemporary understandings of mitochondrial dysfunction, disordered lactate metabolism, and aberrant histone modifications in diabetic nephropathy [62, 63]

Fat-soluble vitamins are handled like lipids and thus are incorporated into chylomicrons that have triglycerides removed by lipoprotein lipase

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While our study has shed light on a prospective protective function for astaxanthin against GUD, further mechanistic studies are needed to rule out the major downstream key players involved in this effect