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These discoveries provide novel therapeutic options for patients with multiple sclerosis, complementing existing immunosuppressive strategies

Sies and Cadenas (1985) introduced the term from the book

ZhouJLuPHeHZhangRYangDLiuQet al

5 10 6 cells transduced with a scrambled shRNA or shACTL6A were inoculated subcutaneously into the hind-flanks of 6-week-old male BALB/ c-nu/nu mice

There are other, perhaps more common, genetic variants associated with the risk of developing ADincluding the late onset form of the disease (LOAD)such as ApoE4 [521, 522] or those identified more recently (e.g., mutations in CD36 [523], see [524] for review)