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[ 4 ] Some small human studies reported improvements in sleep efficiency and sleep latency in chronic insomniacs, though the effects were described as weak and not consistently different from placebo

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No morphological changes were observed in the CA1 and hilus, but there was significant damage in the CA3 and DG that seems to be associated with the cognitive impairments triggered by exposure to 50 mg/L of fluoride

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Treatment with resveratrol (25 mg/kg/day for 14 days in normal conditions) followed by 22 days in the dark prevented the decrease in SIRT1 activity in the liver and skeletal muscle of mice when in the dark [31, 46]