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After two weeks, the rats' weights were recorded before administering any treatment and beginning the experiment

In contrast to physiological ROS signaling, pathologically elevated ROS levels are linked to widespread lipid peroxidation and oxidative injury (Zheng et al., 2022)

plasma contains kidney-synthesized GPx3 for extracellular defense, influenced by selenium availability (Ottaviano et al., 2009)

Clinically, it presents with recurrent diarrhea, bloody, mucopurulent stools, abdominal pain, and tenesmus, and may be accompanied by extraintestinal manifestations such as arthritis and cutaneous lesions (Magro et al., 2017)