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59 Shafei reported that BCAT1 inhibited the Ras/ERK pathway and activates PI3K/AKT pathway through insulin/IGF-1, ultimately promoting the expression levels of FOXO3a and Nrf2 and regulating the proliferation, migration, and invasion in triple-negative breast cancer (TNBC)

doi: 10.1210/er.2001-0039 126

Chronic -radiation-induced senescence and histone reduction rely on TP53 but not ATM To characterise the signalling mechanisms underpinning our observations, we examined the potential role of the tumour suppressor TP53 (p53) due to its key roles in regulating transcription and senescence in response to DNA damage 53,54

Antioxidants normally terminate many reactions by removing free radical intermediates and inhibit other oxidation reactions

BPC-157 is frequently studied for its role in tissue-related signalling models, while TB-500 is associated with pathways involving cellular movement and structural protein interactions , particularly in actin regulation studies