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In yet another embodiment, the macrophage comprises a type 1 macrophage, M1 macrophage, type 2 macrophage, M2 macrophage, M2c macrophage, M2d macrophage, Tumor Associated Macrophage (TAM), CD11b + cell, CD14+ cell, and/or CD11b +/CD14+ cell, optionally wherein the cell and/or macrophage expresses the target

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The Result Patients may follow every instruction, take every medication, and still feel worse exhausted, foggy, swollen, aching