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Collectively, these findings indicate that maternal obesity and GDM may induce long-lasting epigenetic changes at the nc886 locus, potentially altering gene regulation across multiple tissues and contributing to the intergenerational transmission of metabolic risk [165]

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Biochemically, the deposition of intracellular iron, abundance of reactive oxygen species (ROS) and aggregation of lipid peroxides are manifested during the occurrence of ferroptosis[12]