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This is the result of a continuous adaptation of the gonococcus to its diverse ecological niche, an adaptation influenced by the use/misuse of antibiotics in more recent times, and which has mainly involved: i

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New England Biolabs, MA, USA), followed by first-strand cDNA synthesis with the NEBNext Ultra II RNA Library Prep Kit for Illumina (New England Biolabs) and NEBNext Multiplex Oligo for Illumina (New England Biolabs) according to the manufacturers protocols

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