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55 The phase 3 REDEFINE-3 trial will further assess the impact of cagrilinitide/semaglutide on major adverse cardiovascular events in people with obesity (with or without T2DM) and established CVD (clinical trial number NCT05669755

Data availability The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request

Among these, long-term use of macrolide antibiotics has been proven to reduce acute exacerbation occurrence risk, but this treatment strategy also brings potential problems of antibiotic resistance and drug adverse reactions ( DPP1 inhibitors have clear potential advantages in bronchiectasis treatment

However, some small inverse correlations between BDNF and pain/PSD values were seen only in the FM patients

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