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Potential reasons for the lack of immunotherapy response in HGSOC patients may include abundance of immunosuppressive factors in ovarian TME such as infiltration of a variety of immunosuppressive cells such as myeloid-derived suppressor cells (MDSC), cancer-associated fibroblasts (CAFs), tumor-associated macrophages (TAM) and Tregs

Goldners trichrome specifically highlighted bone mineralization dynamics: mineralized bone matrix appeared green/blue, while unmineralized osteoid (newly formed bone) was stained red

[DOI] [PMC free article] [PubMed] [Google Scholar] Wingfield PT, Stahl SJ, Williams RW, Steven AC

J Am Coll Cardiol 82(18):e167

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