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Some studies suggest that consistent use of high-quality milk thistle can show measurable increases in liver glutathione levels within a few weeks, though long-term support is usually recommended for the best outcomes.

MDA levels were normalized against the total protein in PBMCs and reported as M MDA/g protein

Beet root extract has been shown in clinical research to improve time-to-exhaustion, lower the oxygen cost of exercise, and enhance cardiovascular efficiency during endurance activity

Table 3 Interventions targeting the gut microbiota for ameliorating high-altitude-related disorders

However, some patients experience primary or secondary failure due to anti-drug antibodies, insufficient drug levels, or individual differences in the immune environment