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doi: 10.1007/s12192-014-0501-z 73 MkandawireE.Mierek-AdamskaA.StrzenbaumS

Drug resistance in multiple myeloma

Aberrant polyadenylation events within introns of tumor suppressor genes such as DICER1 and FOXN3 result in the production of truncated proteins lacking essential tumor-suppressive functions, thereby promoting tumorigenesis