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An akinetic crisis (AC) or acute akinesia is a life-threatening complication of PD that can be caused by a variety of issues, including infections, medication errors, or failed surgery

However, the general signs of dopamine deficiency include predominantly parkinsonism, and dystonic movements, in young infants also tremorous or choreatiform and various other involuntary movements, while serotoninergic deficiency is thought to manifest as sleep pattern disturbance, mood dysregulation and temperature instability [17]