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Change history 22 October 2025 A Correction to this paper has been published: Abbreviations IPF: Idiopathic pulmonary fibrosis TGF-: Transforming growth factor- Nrf2: Nuclear factor erythroid 2related factor 2 SFN: Sulforaphane AMPK: AMP-activated protein kinase BCS: Bovine calf serum NQO-1: NAD(P)H quinone dehydrogenase 1 HO-1: Heme oxygenase 1 CaMKK2: Calcium-dependent protein kinase kinase 2 NOX4: NADPH oxidase 4 MDA: Malondialdehyde SOD: Superoxide dismutase GSH: Glutathione i.t

The global impact of diabetes is closely connected to the development of early insulin resistance, which stems from impaired signaling at the insulin receptor (INSR)